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The mean eGFRs in the GLP-1 RAs users and non-users groups were 73.2 and 75.9 ml/min/1.73 m 2 , respectively
These long-term effects have led to a rise in Ozempic injury claims, with many plaintiffs stating that drug companies failed to warn about the delayed onset of these serious health risks
Trial data shows tirzepatide achieves higher average weight loss: 20.9% at 72 weeks on 15mg (SURMOUNT-1) versus 14.9% at 68 weeks on semaglutide 2.4mg (STEP 1)
The pathway also downregulates pro-inflammatory cytokines such as IL-1 and TNF- while upregulating anti-inflammatory IL-10, attenuating neuroinflammation
