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Unlike endogenous GLP-1, which is rapidly degraded by dipeptidyl peptidase-4, GLP-1 receptor agonists are resistant to degradation and have longer half-lives, particularly for modern long-acting agents, such as liraglutide, dulaglutide, semaglutide and tirzepatide
The structure, pricing, and medication options are nearly identical
Theoretically, the delayed gastric emptying induced by GLP-1 receptor agonists means that stomach contents remain in the stomach for extended periods
Therefore, current prescribing information advises discontinuation before conception
It supports cell regeneration, collagen production, and angiogenesismaking it a powerful therapeutic for both internal and external injuries
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