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In addition, the absence or decrease in levels of cytosolic GSH resulted in PDI becoming more oxidized, limiting the ability of the enzyme to isomerize nonnative disulphide bonds

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Regulatory review, if trials conclude successfully, could still take several years

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As noted by Mahiques-Santos, the higher incidence of side effects associated with MT-II is due to its being less receptor-specific than MT-I [1]

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Preconditioning limits mitochondrial Ca(2+) during ischemia in rat hearts: Role of K(ATP) channels

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