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The authors point out that the symptoms of simultaneous bilateral AACC may overlap with the flu-like symptoms for which the medications potentially triggering AACC are taken

If genetic testing shows you have variants associated with rapid dose escalation, your pharmacy may recommend having backup vials ready

Although there is a broad clinical spectrum of glutathione synthetase deficiency, manifestations usually include hemolytic anemia, often include metabolic acidosis, and sometimes include progressive neurologic symptoms as well as other systemic signs (eg, respiratory distress, sepsis, hyperbilirubinemia) (62

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