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(2022): Reduced calorie diet combined with NNMT inhibition accelerates obesity reversal in diet-induced obese mice

Pathological causes of elevated B12 warrant careful consideration: Haematological disorders : Myeloproliferative neoplasms (polycythaemia vera, chronic myeloid leukaemia), acute leukaemia, and lymphoproliferative disorders can increase B12-binding proteins (transcobalamin and haptocorrin), elevating total serum B12 [3] Liver disease : Hepatocellular damage releases stored B12 into circulation

That said, always check with your provider before adding new therapies to your regimen to avoid unnecessary overlap or interactions

Additionally its also suppressed my appetite considerably

Either copper peptide alone works if availability or tolerance is a constraint