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The demand for Se will increase after suffering environmental pressures, and supplementation is a necessary condition to meet the needs of fish growth (Nasir et al., 2015) and lack may have adverse effects on fish health, leading to tissue damage and physiological function weakening (Khan and Bano, 2016)
It also helps regulate nitric oxide production, which plays a key role in reducing inflammation and supporting circulation to injured or stressed tissues
Similar mechanisms in which the GSH-thiolate acts as a Brnsted base catalyst have been suggested for the well-studied isomerization of ketosteroids by GST A3-3 43 (Extended Data Fig
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