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Graefe-Mody, U

In a double blinded randomised study, daily injections of semaglutide (0.4 mg) in obese patients resulted in an average of 14% decrease in body weight, over placebo, after a year

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Barnett C, Costill DL, Vukovich MD, Cole KJ, Goodpaster BH, Trappe SW, Fink WJ

Regional Analysis North America led the GLP-1 market with a 57% share in 2025, due to the high prevalence of obesity and type 2 diabetes, alongside a healthcare system where there is early access to new medications via the FDAs fast-track pathway and extensive insurance that makes such expensive medications accessible to millions of patients