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The Journal of Clinical Investigation , 130 (7), 38653884

[57] demonstrated that GLP-1 based agents were associated with a three-fold increased risk of pancreatic enzyme elevation relative to controls, yet did not indicate a significant rise in pancreatitis or pancreatic cancer
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Our study indicates the importance of IGF-1R in maintaining a balance between cell survival and apoptosis of GNE deficient cells that are of interest to be explored further for drug design in disorders associated with sialic acid deficiency

Citrus juice inhibits the enzyme only within the intestines if consumed in small amounts

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