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Spatial analyses have shown that necrotic regions display significantly greater local propagation activity than apoptotic regions, indicating that the mode of death execution itself may govern the transition from isolated cell death to multicellular ferroptotic contagion
The aforementioned cytokines act through the mitogen-activated protein kinase (MAPK) and NF-B signaling pathways
Luethcke KR, Ekena J, Chun R, Trepanier LA
The red arrows in Figure 1 show what we call long-range interactions, in which substrates allosterically affect distant enzymes in the network
The mixture of hA3A-eBE3-Y130F mRNA (100 ng/L) and Trim37- sgRNA-stop (100 ng/L) was diluted in RNase-free water, centrifuged at 13,400 g for 10 min at 4 C, and injected into the cytoplasm of zygotes ( mTmG Blimp1-T2A-Cre or B6D2F1 Nanog-EGFP ) using a micromanipulator (Olympus, Tokyo, Japan) and a FemtoJet microinjector (Eppendorf)
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