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Figure 2 On the other hand, it has been reported that activated PKA can limit the levels of cAMP by either the stimulation of phosphodiesterases (PDE) ( Figure 2 ), or through the desensitization of some GPCRs (36, 4042)

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c , BN-PAGE immunoblot on isolated WAT mitochondria from Control and Bmal1-KO mice at ZT14 using an antibody mix against OXPHOS complex subunits (n = 4)