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To view or add a comment, sign in Excimer Laser for Plaque Psoriasis: A Systematic Review and Meta-analysis A JDD metaanalysis of 308 nm excimer laser treatment for plaque psoriasis pooled four clinical trials (patients treated twice weekly for greater than or equal to 10 sessions, PASI used as the outcome) and found a statistically significant improvement in disease severity (standardized mean change SMCC -5.94

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Lipid profile improvements (TRIUMPH-4): Non-HDL cholesterol: Clinically meaningful reduction Triglycerides: Significant reduction hsCRP (inflammatory marker): Significant reduction HDL cholesterol: Not significantly improved (consistent with Phase 2 findings) The triglyceride reduction is particularly notable and likely related to glucagon receptor activation, which enhances fat oxidation