While average plasma glutathione levels were slightly higher with SAG, erythrocyte glutathione levels were somewhat lower compared to regular glutathione (Cavallaro et al., Int J Clin Nutr Diet, 2018) [17]
Mahmood et al., 2010
Indeed the activation of prodrugs in GST overexpressing cells may lead to high concentrations of an active drug, as compared to normal cells with moderate enzyme levels
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doi:10.1097/HJR.0b013e32828622d7 Sasaninia K, Kelley M, Abnousian A, et al
