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48 GSH levels were determined within the volume of interest using MEGA-PRESS double-editing for the cysteinyl -CH 2 residue of GSH 7 (repetition time=2,000 ms, echo time=122 ms, free induction decay points=2,048, spectral width=2,000 Hz, number of averages=8 per phase cycle ON or OFF, 320 acquisitions total requiring just under 11 min)
Third, tumor heterogeneity means that different cancer types or even cells within the same tumor may vary in their dependence on GSH, making a single-target strategy insufficient
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The decreased cardiovascular risk might be explained by a reduced dietary methionine supply in subjects with intact vitamin stores