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Liraglutide activates the PKA/CREB pathway in the cartilage tissues of the knee OA rat model Western blot analysis was also used to detect the expression of PKA/CREB pathway components in the cartilage tissues of OA knees after treatment with liraglutide or saline
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GIP GLP-1-,
The headline result was a mean 17.5% body-weight reduction at 24 weeks in the 12 mg arm, with clear dose-response behavior across the four active doses
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