Clinical data shows that 15% of patients on the highest dose of semaglutide may eventually need to switch to a dual agonist like tirzepatide to re-engage their metabolism
doi: McGuire FP, Martinez R, Lenz A, Skinner L, Cushman DM
doi:10.1056/NEJMoa2502081 Jastreboff AM, Kaplan LM, Frias JP, et al
A notable proportion of patients achieve clinically significant weight loss, with studies indicating that around 40% of adults lost at least 5% of their body weight after one year, and over 15% lost at least 10%
So, we must find alternative ways to soothe ourselves when feeling challenging emotions like stress, loneliness, or sadness