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Most people begin at lower doses and increase at intervals set by your prescriber, commonly about every 4 weeks until they reach their therapeutic dose, the level where weight loss becomes consistent and side effects feel manageable
That endpoint matters because pain is not cosmetic
Gradual dose titration allows the body to adjust to semaglutide, helping reduce gastrointestinal side effects as doses increase
On the other hand, when patients discontinue GLP-1s, their weight regain is typically incremental to how quickly and how much they lost while taking the medicine, Buie said
Wegovy typically costs more due to its packaging, single-dose pen design, and higher prescribed dose
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