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Cell-mediated immunity plays a central role, with nave CD4 + T cells differentiating into effector subsets upon antigen recognition: Th1 cells secrete IFN-, IL-2, and TNF-, inducing MHC class II expression and promoting Fas-mediated apoptosis of thyrocytes

The most widely used therapy is local steroid and narrowband ultraviolet B monotherapy (Grimes and Nashawati 2017), they are not effective in all patients and are expensive, not easily accepted, and are associated with side effects (Huo et al., 2014)

Adv Pharmacol 38:229246

Supplementing with organic glutathione has been shown to

LRK and LIL wrote the manuscript