GLP-1 drugs research: summary GLP1 drugs may move beyond diabetes and weight loss into multidisease therapies This could significantly increase the number and profile of users, including nonobese and older populations Innovations such as oral GLP1s may further accelerate uptake and accessibility For food and beverage, the shift needs to be watched closely to understand behaviour change, consumption patterns and nutritional needs GLP-1s started life as diabetes medications, then took the world by storm for treating obesity

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These findings underscore that GIP agonism and antagonism represent two distinct, context-dependent strategiesthe former enhancing insulin secretion and metabolic flexibility under physiological stimulation, and the latter mitigating GIPR overstimulation in obesity-associated insulin resistance [42,47]
This has changed with some of the new medications that have recently become available
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