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Further randomized controlled clinical researches should be designed to evaluate the use of a specific combination of antioxidants in chemotherapy and determine optimal doses of antioxidants for specific cancer setting to prevent chemotherapy-induced ovarian failure

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And one of the hardest to diagnose without access to analytical chemistry tools like HPLC

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The repercussions of these mitochondrial ROS include potential damage to neighboring structures, including mitochondrial DNA, which is vulnerable to oxidative harm