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In a mouse model of tumor-associated inflammation in which the antitumor effects of antigen-specific CTLs are eradicated by expression of IL-1 in the tumor cells, we determined that therapeutic failure was not caused by more profound suppression of CTLs by IL-1expressing tumors than tumors not expressing this proinflammatory cytokine
doi: 10.1016/j.phanu.2020.100190
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PMID 30521681
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