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Reaching HBV-DNA negativity is an important milestone in the treatment of chronic hepatitis B, as it is associated with reduced viral replication and liver inflammation
Long-term: 20 C or colder, sealed, desiccated, dark Short-term transit: ambient temperatures are generally tolerated by lyophilized material for short periods, though cold-chain shipping remains preferable Critical habit: allow the vial to reach room temperature before opening
Whether this newly described pathway has implication in mammals needs further verification
Trends Endocrinol Metab (2015) 26(5):24855
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