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Others may need diagnostic evaluation before any therapy is considered

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The main things to watch are overlapping side effects, since both can cause nausea or GI upset, and the fact that GLP-1 drugs slow stomach emptying, which can slightly affect how oral medicines are absorbed

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And supplements marketed as boosting GLP-1 levels lack clinical evidence that they work in humans, at least by any measure that parallels the effects of prescription GLP-1 drugs, said Pieter Cohen, an associate professor of medicine at Harvard Medical School

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