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Chem Res Toxicol 1999
Specifically, 1 mL (100-unit) insulin syringes with a 29-31 gauge needle
Efficacy is slightly reduced in those with diabetes, but participants were still able to lose 16.9% of body weight alongside a 2.16% reduction in HbA1c from baseline after 36 weeks [118]
In a 26-week rat oral toxicity study, AOD-9604 produced dose-dependent changes in serum osteocalcin (a bone-turnover marker) at week 13, with the direction reversing by week 26
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