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Researchers have found that only around 40% of people are able to produce urolithin A due to differences in individual gut microbiomes.6 Fortunately, other studies have found that the remaining 60% of people can overcome that limitation through supplementation.12 Most of the potential benefits of urolithin A are attributed to the compounds effects on mitophagy.7 This is when your body cleans up damaged or excess mitochondria,8 then replaces them with new, healthy ones to maintain mitochondrial homeostasis.14 As you age, the rate and effectiveness of the mitophagy process decrease

This is often described as a "GH bleed" effect

Value Chains of Botanical and Herbal Medicinal Products: A European Perspective

However, more research is necessary to confirm the efficacy of vitamin E supplementation as an adjunct treatment for glaucoma, particularly through human clinical trials (132)

The Food and Drug Administration also hasnt approved it