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A thorough assessment of other potential causes is essential before attributing leg cramps specifically to semaglutide therapy
Reliable information should explain what is known, what is still uncertain, and what should not be assumed
The FDA's 2023 guidance clarified which compounded GLP-1 products remain legal, and licensed 503A compounding pharmacies continue to produce semaglutide under strict pharmaceutical standards
For many patients this helps reduce "food noise," improve satiety, and make eating patterns easier to manage
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