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In 2005, exenatide was approved as a kind of GLP-1 receptor agonists (GLP-1RAs) for the clinical treatment of type 2 diabetes mellitus (T2DM) as the first international incretin drug [6]

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This condition causes oxidation of low-density lipoprotein, diminishes nitric oxide synthesis and leads to arterial stiffness, endothelial inflammation and foaming

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Endothelial cell-derived hemangiosarcomas can be induced in rats and mice by a wide range of industrial, natural, and pharmaceutical compounds

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Therefore, our results suggest the unique importance of understanding the metabolomic problems that occur early in the diseased motor cortex, and encourages for the development of novel therapeutic strategies by reestablishing the perturbed NAD + levels in the brain

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The above bracket represents a two-way ANOVA analysis of treatment interaction between the normal C57BL/6J mice and MIA mice

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