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19.7% on tirzepatide hit 30% weight loss vs

doi: 10.1038/sj.cr.7310095

BMI of 27 or greater: Classified as overweight and having at least one weight-related medical condition, such as: Type 2 Diabetes or Prediabetes

The STEP-HFpEF trial randomised 529 patients with obesity (BMI 30 kg/m 2 ), HFpEF (left ventricular ejection fraction [LVEF] 45%) and New York Heart Association (NYHA) Class II symptoms to once-weekly subcutaneous semaglutide 2.4 mg or placebo

Acknowledgements We sincerely thank Ya-Hui Tsai, PhD, research specialist in the Division of Pediatric Surgery, Department of Surgery, Far-Eastern Memorial Hospital for editing the figures in the manuscript