Everard A, Belzer C, Geurts L, Ouwerkerk JP, Druart C, Bindels LB, et al
[7] [10] If sleep disturbances are significantly affecting your wellbeing, your clinician may consider adjusting your tirzepatide dose, temporarily pausing treatment, or exploring alternative therapeutic options
The combination group included those who added a newer generation GLP-1RA (i.e., exenatide once weekly [OW], dulaglutide, semaglutide OW T2D, or oral semaglutide) or dual GLP-1/GIP agonist (tirzepatide T2D) to their SGLT2i (i.e., canagliflozin, dapagliflozin, empagliflozin, ertugliflozin, or bexagliflozin) treatment, with persistent use of a GLP-1RA and SGLT2i for 180 days each and an overlap 120 days, where the gap after exhaustion of days supply was required to be 30 days
There are side effects
Many patients find that workouts feel best in the morning or early afternoon, after a light breakfast or snack