This system achieves active targeting via CD44-mediated selective recognition of renal tubular epithelial cells and M1 macrophages expressing CD44, and triggers ROS-responsive release in an oxidative stress microenvironment
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Cui, H., Feng, C., Zhang, T., Martnez-Ros, V., Martorell, P., Tortajada, M., Cheng, S., Cheng, S., & Duan, Z
and Bost, F
These deamidated NAD + metabolites are circulated to the liver and kidney, significantly contributing to the bulk of NAD + biosynthesis