Meanwhile, in comparison to the control group, GHK-Cu accelerated the regeneration of nerve fibers from nerve stubs placed in a collagen tube, increased the number of axons and the proliferation of Schwann cells, and boosted the synthesis of nerve growth factor and the neurotrophins NT-3 and NT-4 [23]
10.1083/jcb.33.2.437 36 DhuriyaY
(Baltim.) 100 , e26086 (2021)
Meanwhile, the outer membrane will rupture, and proteins, such as cytochrome c and apoptosis-inducing factor (AIF), will be released from the intermembrane space into the cytosol, triggering apoptosis [190, 191]
The combination addresses skin aging from multiple angles