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However, the peptide is degraded by the enzymes DPP-IV and neutral endopeptidase 24.11 ( GLP-1 is a multifaceted peptide that can modulate alcohol-related responses
In male mice, this alcohol-induced mCPP is blocked by the GLP-1R agonists Ex4 and GLP-1 (Shirazi et al., 2013), whereas liraglutide does not have this ability (Vallof et al., 2015)
Dose reduction or temporary discontinuation of antihypertensive agents may be necessary
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