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The muscle preservation argument Weight loss from GLP-1 agonists typically includes 25 to 40% lean tissue loss

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It has been shown to upregulate pathways tied to collagen and glycosaminoglycan synthesis, modulate metalloproteinase (MMP) and tissue inhibitor of metalloproteinases (TIMP) balance, and support antioxidant effects, thereby contributing to matrix organization and structural stability in research settings

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