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Sood B et al

That includes proactive management of side effects, candid conversations about the long-term nature of treatment, infrastructure to identify and support patients at risk of stopping and addressing the cost barriers that make GLP-1 therapy unsustainable for many.

Steffen M, Sarkela TM, Gybina AA, Steele TW, Trasseth NJ, Kuehl D, et al

Patients who successfully implement and sustain meaningful dietary changes, regular physical activity, and behavioural strategies may have better outcomes if treatment is reduced or stopped

Potential adverse effects, such as gastrointestinal issues and long-term safety concerns, also limit widespread adoption