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When averaging together information from more than 100,000 people, the presence of an Lp(a) genetic variant caused an average decrease in lifespan of 1.5 years.[ref] This doesnt mean everyone with high Lp(a) dies early

This also means that some of the improvements persist after discontinuation, because the new synaptic connections Dihexa helped create remain in place

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They were randomly assigned in a 2:1 ratio, to 68 weeks of treatment with semaglutide (at a dose of 2.4 mg) or placebo, plus lifestyle intervention

Genotoxic effect of bile acids on human normal and tumour colon cells and protection by dietary antioxidants and butyrate