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To test the hypothesis that a disorder of ROS homeostasis is induced by OsG-produced oxidative stress, an antioxidant, GSH (50 mg/kg/ 6 h), was subcutaneously injected into animals with LOsG challenge as described above, defined as the LOsG.TdGSH group ( n = 10)

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Here, in the alveolar sacs, the epithelial barrier becomes extremely thin and its surface mucus becomes replaced by surfactant, a detergent-like substance that prevents alveolar collapse when we breathe (25)