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Such a non-protein cofactor is known as a "prosthetic group." R -lipoic acid functions as a prosthetic group for the biological activity of the following multienzyme complexes: The glycine cleavage system that catalyzes the decarboxylation of glycine coupled with the addition of a methylene group (-CH 2 ) to tetrahydrofolate to form 5,10-methylene tetrahydrofolate, an important cofactor in the synthesis of nucleic acids ( Figure 3 )

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Studies show it lowers ACTH levels in healthy men without impacting cortisol, suggesting it may help manage stress

The hamstring tendons attach at the ischial tuberosity (sitting bone), and this junction frequently develops chronic degenerative changes in runners and other athletes

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