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Consistent with the observation in vivo , sulforaphane alone did not affect LC3-II expression, but significantly rescued rotenone-inhibited LC3-II expression

as a result, this study is a complete study because it can analyse drug, toxic metabolite, and antidote in one analytical run

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By transcriptionally activating serine synthesis enzymes, Np63 establishes a metabolic dependency that sustains nucleotide synthesis, redox balance, and DNA damage tolerance

Pharmacokinetics The effective therapeutic range for plasma valproic acid levels is 40-100mg/L