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6.5 Mitochondria as a central platform for immune signaling and pathogen recognition Mitochondria function as central hubs that integrate metabolic regulation with innate immune signaling, coordinating host defense against diverse pathogens
Obesity is one of the strongest risk factors and predisposition for type 2 diabetes (169, 171)
Int J Epidemiol 49(3):740741e
Figure 3C), and HOMA-IR ( = 0.046, = 0.060
This hypothesis proposes that small vessel disease in brain regions controlling mood contributes to depression, particularly in older adults
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