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xCT inhibition by sulfasalazine or through siRNA targeting SLC7A11 leads to reduced cell proliferation in vitro and in-vivo via reduction in GSH levels and an increase in ROS by inhibiting the CD44v9-SLC7A11 interaction (111, 113)
haematobium 28-kD glutathione S-transferase (rSh28GST), the first vaccine to enter a clinical trial for urinary schistosomiasis, has failed due to its lower safety and immunogenicity ( S
Scientists are studying them as potential treatments for addiction and dementia
Sherif NA et al
Beneficial effects of fecal microbiota transplantation in recurrent Clostridioides difficile infection
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