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Reynolds, E., Bottiglieri, T., Laundy, M., Stern, J., Payan, J., Linnell, J., & Faludy, J

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Therefore, the efficacy-to-cost ratio of helping patients to achieve a weight loss of 5% was better with once-weekly semaglutide 1 mg than with exenatide ER 2 mg, dulaglutide 1.5 mg and liraglutide 1.2 mg

One consideration specific to peptide stability deserves mention

This hypothesis has not been tested for retatrutide but is supported by data from other nasally delivered GLP-1 agonists