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This catalytic reaction of GPX4 follows a tert-uni ping pong mechanism, involving redox reactions of the selenocysteine (Ursini and Bindoli, 1987)
Lenz, L
doi: 10.1016/j.molmet.2024.101880 244 Re CecconiADBaroneMFortiMLunardiMCagnottoASalmonaMet al
2024 May 14;331(18):1519-1521
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