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becomes particularly relevant, and the answer truly varies depending on a few key factors: The Underlying Cause of Deficiency: The Underlying Cause of Deficiency: Pernicious Anaemia/Malabsorption: For those with an inability to absorb B12 orally (like in pernicious anaemia), injections are typically a lifelong treatment
No Human Pharmacokinetic Data Pharmacokinetics how a compound is absorbed, distributed, metabolized, and eliminated determines whether a dose produces any effect and what that effect is
Therefore, high serum B12 levels in individuals supplementing with B12 are typically harmless and do not cause adverse health effects