In practice, the long-acting GLP-1 RAs became preferred for general glycemic control due to convenience and greater A1c reduction, whereas short-acting ones like lixisenatide found a niche in combination products or for targeting post-meal glucose excursions (for instance, some use lixisenatide mainly to handle breakfast hyperglycemia)
GLP-1 injections can cause discomfort at the injection site
In a 2-year long carcinogenicity study in mice, subcutaneous doses of 0.3, 1, and 3 mg/kg/day were administered in males
Medications that commonly promote weight gain include certain antipsychotics, antidepressants (particularly mirtazapine and paroxetine), corticosteroids, insulin, sulfonylureas, some beta-blockers, and anticonvulsants like gabapentin
Metabolism controls how our bodies turn food into energy