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For the open-label treatment extension period analysis, only the efficacy estimand was used due to the lack of a true placebo group

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The dose may then be increased gradually if needed

People with Parkinsons disease, which is marked by muscle stiffness and tremors in the hands, arms, legs, or jaw, are at an increased risk of developing RLS, according to John Cline, PhD, a Connecticut-based licensed clinical psychologist specializing in sleep medicine and a diplomate of the American Board of Sleep Medicine