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293 PK deficiency may be also caused by mutations not directly involving the PKLR gene as demonstrated by a deficiency of PK being one of the key features of severe congenital hemolytic anemia caused by mutations in the key erythroid transcription factor KLF1

1 Newer technologies used to evaluate DNA fragmentation and other sperm components, though not yet routinely used, may also inform the treatment approach

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Sleep quality also affects digestive function, making consistent sleep schedules (7-9 hours nightly) an important component of comprehensive symptom management

190 , 400411 (2020) M