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Potential downsides Although current dual and triple agonists have not seen any long-term harmful effects so far, it is a possibility worth considering, given the history of anti-obesity drugs

Some reported side effects of peptides may include water retention, numbness in the hands and feet, and increased fatigue

One view would be that the mouse does not recapitulate the effects of dulaglutide in the human heart: in the atria of adult mice (there may well be developmental or disease related other findings) dulaglutide did not increase force

Without a PCP managing your care alongside the program, having a physician who actively monitors your response and adjusts your protocol becomes even more important

How your body responds, the food you choose, your activity level, and even sleep and stress will all play a role in how much weight you can lose