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In the case of psoriasis, the immune system triggers an overproduction of skin cells, leading to their rapid accumulation on the skins surface

Appetite signals can begin, but measurable weight change in the first week was not a documented trial outcome

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These provide the most objective assessment of both efficacy and side effect burden

One individual per group was euthanized before addressing the next animal in each group to render differences arising from the time of day at euthanization (e.g., cecal mass changes resulting from differences in time post-food consumption) comparable across all groups