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From gastric model to a broadening preclinical program (1990s2000s) After the 1993 paper, the Zagreb group published a sustained series of rodent studies

Oxidative stress and altered antioxidant defenses in children with acute exacerbation of atopic dermatitis

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Potential therapeutic targets are low-grade systemic inflammation, oxidative stress, NO signaling, RAAS signaling, ECM remodeling, calcification, VSMCs, and cellular senescence