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In reality, GLP-1 RAs are primarily used to treat diabetes and obesity
In the AWARD 11 trial, patients using semaglutide (1 mg weekly) achieved greater weight reduction than those using dulaglutide (3 mg weekly), with a mean difference of approximately 0.24% points
This directly targets adipose tissue, particularly in areas where fat is most resistant to conventional diet and exercise
If you use oral hormonal contraceptives, discuss this with your prescriber, as data from the tirzepatide SmPC suggest that additional contraceptive precautions may be advisable during initiation and dose escalation of GLP-1/GIP-based therapies, pending specific retatrutide data
Constipation occurs because semaglutide slows gastric emptyingthe same mechanism that keeps you feeling full
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