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We found both human and mouse -cells and -cells express the complete catecholamine signaling machinery, though with major cell type- and species-specific differences (Fig
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Furthermore the pH-dependent enlistment of GDH2 isoform alone (push mechanism) or accompanying GDH 1 flux (anaplerosis driven pull mechanism) would provide regulatory options in responding to anaplerotic/cataplerotic and, or, acid /base demands in tumors
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The crosstalk between glutathione metabolism and non-coding RNAs in cancer progression and treatment resistance
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